Icotinib is a small molecule targeting epidermal growth factor receptor tyrosine kinase, which shows non-inferior efficacy and better safety comparing to gefitinib in previous phase III trial.The Upright Freezer present study was designed to further evaluate the efficacy and safety of icotinib in patients with advanced non-small-cell lung cancer (N

Industry 4.0 digitization requirements have led to widespread adoption of industrial wireless sensor networks (IWSNs) in manufacturing environments.These require strict control of the traffic flowing over the network to ensure the quality of service.Software-defined networks (SDNs) can address this challenge, as their centralized operation allows r

Fusarium neocosmosporiellum (formerly Neocosmospora vasinfecta) is a cosmopolitan fungus that has been reported from soil, herbivore dung, and as a fruit- and root-rot pathogen of numerous field crops, although it is not known to cause significant losses on any crop.Taking advantage of the fact that this species produces prolific numbers of perithe

Anita Gupta1, Sarah Daigle2, Jeffrey Mojica3, Robert W Car Sunshade Hurley41Pain Management Division, Department of Anesthesiology, University of Pennsylvania School of Medicine, Philadelphia, PA, USA; 2Department of Anesthesiology and Critical Care, 3Department of Anesthesiology and Critical Care, Division of Pain Medicine, University of Pennsylva

Abstract Background This study aimed to investigate the biomechanical effect on the Takeuchi classification of lateral hinge fracture (LHF) after an opening wedge high tibial osteotomy (HTO).Methods We performed an FE simulation for type I, type II, and type III in accordance with the Takeuchi classification.The stresses on the bone and plate, wedg